استفاده از اکترئوتاید در جراحی های دستگاه گوارش

Almost all major gastrointestinal operations should have some sort of mechanical drainage by a nasogastric tube suction in order to keep the system at rest and prevention of gastric dilatation. The rational behind this preliminary study was to inhibit the secretions medically rather than to drain it mechanically ,by injections of somatostatin analogue (octreotide) 100 mg half hour before removal of nasogastric suction tube on the first post-operative day and continue it for three days every eight hour S. C. . We used this treatment protocol as a pilot study on ten patients with results far better than expected. Above all they were able to eat second day after surgery, and needed far less narcotics postoperatively. We also used ten patients as our control group with almost the same ages and similar operations, although all patients undergoing gastrointestinal surgery could be considered as control group. In our treated group not only they had less discomfort and other complications due to nasogastric tube, but overall about 1000c.c of G.I. secretions remained and preserved in their G.I. systems instead of being pumped out from gastrointestinal tract.